Analysis of cancer cell behaviour using sub-THz excitation in COMSOL Multiphysics

Monodipa Sarkar (2)1, Aayushi Sinha (1)2, Niraj Kumar (3)3
1Vacuum Electron Devices Design Group, Academy of Innovative and Scientific Research (AcSIR), Ghaziabad, India,2001002
2 Amity Institute of Biotechnology (Autonomous) , Amity University Noida, India, 201303
3Vacuum Electron Devices Design Group(CSIR-CEERI, Pilani) , Academy of Innovation and Scientific Research (AcSIR) Ghaziabad, India,2001002
Published in 2023

In this paper, analysis of cancer cell using Sub-THz technology have been studied. Sub-THz technique for cancer detection is a much reliable and safer technique as compared to conventional methods [1,2]. To study the behavior of cancer cells and normal cells using Sub-THz technology, a simulation model has been developed using COMSOL software [3]. In COMSOL Multiphysics, the 3D modeling of the cancer cell kept inside the waveguide has been designed using RF module. The waveguide taken in the simulation model is WR-10, with frequency range of 75 GHz to 110 GHz with step size 0.1 GHz, while the cancer cell is placed in center of waveguide. The difference in transmissive and reflective property of cancer cells and normal cells have been analyzed. The comparative analysis has been performed for these different cells by shining the sub-terahertz signal. The resultant S-parameter clearly depicts the difference in reflection and transmission parameter property of cells.

REFERENCE 1. Yan Peng, Chenjun Shi, Xu Wu, Yiming Zhu, and Songlin Zhuang, “Terahertz Imaging and Spectroscopy in Cancer Diagnostics: A Technical Review” AAAS BME Frontiers Volume 2020, Article ID 2547609, 2020. 2. Hwayeong Cheon, Hee-Jin Yang, and Joo-Hiuk Son, “Toward Clinical Cancer Imaging Using Terahertz Spectroscopy”, IEEE Journal of Selected Topics in Quantum Electronics, Vol. 23, No. 4, 2017. 3. https://www.comsol.com/

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