研究開発におけるマルチフィジックスシミュレーションの具体例

さまざまな業界のエンジニア, 研究者, 科学者がマルチフィジックスシミュレーションを使用して革新的な製品の設計とプロセスを研究および開発しています. COMSOL カンファレンスで発表したテクニカルペーパーやプレゼンテーションからインスピレーションを得てください. 以下の選択項目を参照するか, クイック検索ツールを使用して特定のプレゼンテーションを検索するか, アプリケーション領域でフィルタリングします.


COMSOL コンファレンス 2020 論文集を見る

Chemical Reaction Engineeringx

Finite Element Modeling of Vasoreactivity Using COMSOL Multiphysics® Software

J. Parikh[1], A. Kapela[1], N. Tsoukias[1]
[1]Biomedical Engineering Department, Florida International University, Miami, FL, USA

Localized calcium events in the endothelial cells (EC) can modulate smooth muscle cell (SMC) calcium (Ca2+) and membrane potential dynamics through release of endothelium derived hyperpolarizing and relaxing factors. Ca2+ levels in the smooth muscle cell (SMC) determine its contractile ... 詳細を見る

An Overview of Impellers, Velocity Profile and Reactor Design

P. Patel[1], P. Vaidya[1], G. Singh[2]
[1]Indian Institute of Technology Bombay, Mumbai, Maharashtra, India
[2]Indian Oil Corporation Limited, Faridabad, Haryana, India

This paper presents a simulation approach to develop a model for understanding the mixing phenomenon in a stirred vessel. The mixing in the vessel is important for effective chemical reaction, heat transfer, mass transfer and phase homogeneity. In some cases, it is very difficult to ... 詳細を見る

Modeling and Simulation of Drug Release through Polymer Matrices

V. Runkana[1], A. Pareek[1], P. Arora[2]
[1]Tata Consultancy Services, Pune, Maharashtra, India
[2]Indian Institute of Technology Delhi, New Delhi, Delhi, India

Limited drug efficacy, undesirable temporal changes in drug concentration and patient non-compliance due to frequent dosing schedule have given impetus to design of controlled drug release systems [1]. Biodegradable polymers due to their favorable and tunable properties and ... 詳細を見る

Network-of-Zones Model for Stirred Tank with Fractal Impeller

G.M. Mule[1], A.A. Kulkarni[1]
[1]CSIR - National Chemical Laboratory, Pune, Maharashtra, India

Stirred tanks are widely used in the pharmaceuticals, chemical and paint industries for variety of operations. The fractal impeller is an impeller having a novel design, developed by CSIR-National Chemical Laboratory, Pune, India. The power number of fractal impeller is relatively lower ... 詳細を見る

Microvascular Dysfunction in PAD Patients

K. Cluff[1], H. Mehraein[1], B. Jayakumar[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment ... 詳細を見る

Modeling of Hydrogel-Based Controlled Drug Delivery System for Breast Cancer Treatment

K. Cluff[1], L. Saeednia[2], H. Mehraein [1], R. Asmatulu[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA

Polymeric hydrogel is a promising class of drug delivery systems with the controlled release behavior in the body. In-situ forming hydrogels can be injected into the body as a fluid which forms a gel within the body tissue and improve the efficacy of the drugs. Various polymers have been ... 詳細を見る

Simulation and Experimental Analysis of Drug Release Rates from Magnetic Nanocomposite Spheres

L. Saeeednia[1], H. Mehraein[2], F. Abedin[1], K. Cluff[2], R. Asmatulu[1]
[1]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
[2]Department of Bioengineering, Wichita State University, Wichita, KS, USA

Targeted drug delivery systems have been wildly studied in cancer therapy due to the toxicity of most of chemotherapeutic drugs. Nanoparticles can be attached to the small molecules of the drugs and serve as drug carriers to deliver the drug molecules into the area of interest. In this ... 詳細を見る

Three-Dimensional Percolation Properties Simulation of a Marine Coating Based on Its Real Structure Obtained from Ptychographic X-Ray Tomography

B. Chen[1], M. Guizar-Sicairos[2], G. Xiong[1], L. Shemilt[1], A. Diaz[2], J. Nutter[1], N. Burdet[1], S. Huo[1], F. Vergeer[3], A. Burgess[4], I. Robinson[1]
[1]London Centre for Nanotechnology, University College London, London, UK
[2]Paul Scherrer Institute, Villigen, Switzerland
[3]AkzoNobel Co. Ltd., Sassenheim, Netherlands
[4]AkzoNobel (UK) Co. Ltd., Tyne and Wear, UK

We present quantitative nano-scale analysis of the 3D spatial structure of an anticorrosive aluminium epoxy barrier marine coating obtained by ptychographic X-ray computed tomography (PXCT) [1-3]. We then use COMSOL Multiphysics® software to perform simulations on the acquired real 3D ... 詳細を見る

Residence Time Distribution for Tubular Reactors

L. R. de Souza Jr.[1], L. Lorenz[1]
[1]Universidade Federal do Paraná, Curitiba, Paraná, Brazil

In the core of Chemical Engineering is the reactor design that includes most of all scientific disciplines. The reactors, in general, are treated ideally. Unfortunately, it is observed in the real world a very different behavior from that expected. Thus, to characterize nonideal ... 詳細を見る

An Approach to Modeling Vacuum Desorption

C. F. Gomez[1], R. Schunk[1], R. F. Coker[1], J. Knox[1]
[1]NASA Marshall Space Flight Center, Huntsville, AL, USA

The objective of this simulation effort is to develop a mathematical model of vacuum desorption on a POC (Proof of Concept) canister loaded with Zeolite 13X/5A . This canister contains a pelletized adsorption bed which is used to adsorb H2O and CO2. Once this bed is fully saturated with ... 詳細を見る