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Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Can Oscillatory Convection Accelerate Signal Propagation in Simple Epithelium?

M. Nebyla[1], M. Pribyl[1]
[1]Institute of Chemical Technology, Prague, Department of Chemical Engineering, Prague, Czech Republic

We introduce a mathematical model of signal transmission in simple epithelial layers. The mathematical model consists of reaction-transport equations for extracellular ligands, cellular receptors, ligand-receptor complexes and a ligand releasing protease. We consider diffusion and nonstationary convective transport of protein ligands in the extracellular space. The study was carried out using ...

Updated Results of Singlet Oxygen Modeling Incorporating Local Vascular Diffusion for PDT - new

R. Penjweini[1], M. M. Kim[1], T. C. Zhu[1]
[1]Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA

Introduction: Singlet oxygen (¹O₂) has a critical role in the cell-killing mechanism of photodynamic therapy (PDT). Therefore, in this study, the distance-dependent reacted ¹O₂ is numerically calculated using finite-element method (FEM). Herein, we use a model [Ref. 1] that has been previously developed to incorporate the diffusion equation for the light transport in tissue and the macroscopic ...

Chemical Reactions in a Microfluidic T-Sensor: Numerical Comparison of 2D and 3D Models

R. Winz[1][2], N. Schröder[1], W. Wiechert[1], and E. von Lieres[1]
[1]Institute of Biotechnology 2, Research Centre Jülich, Jülich, Germany
[2]Research Center for Micro and Nanochemistry, University of Siegen, Siegen, Germany

In recent years lab-on-microchip technology has become a powerful tool for micro-scale analysis of biochemical processes. In the studied system the overall process consists of transport, convection, diffusion, reaction and adsorption processes. Two compounds A and B, contained in a carrier fluid (buffer), are introduced into a reaction channel via a Y-shaped double-inlet. As the streams flow ...

Advancements in Carbon Dioxide and Water Vapor Separations Using COMSOL Multiphysics® Software - new

J. Knox[1], R. F. Coker[1], C. F. Gomez[1], R. Schunk[1], R. Cummings[1]
[1]NASA Marshall Space Flight Center, Huntsville, AL, USA

NASA's Advanced Exploration Systems (AES) program is pioneering new approaches for rapidly developing prototype systems, demonstrating key capabilities, and validating operational concepts for future human missions beyond Earth orbit" [1]. Under the new Atmosphere Revitalization Recovery and Environmental Monitoring (ARREM) project [2], efforts are focused on improving current state-of-the-art ...

Finite Element Analysis of Induced Electroosmotic Flow in Brain Tissue and Application to ex vivo Determination of Enzyme Activity

Y. Ou[1], A. Rupert[1], M. Sandberg[2], S. Weber[1]
[1]University of Pittsburgh, Pittsburgh, PA, USA
[2]University of Gothenburg, Gothenburg, Sweden

Ectopeptidases are commonly accepted to be a means of clearing active peptides. However, studies have shown that they can also regulate peptide activity. We have developed a technique of electrokinetic push-pull perfusion (Ek-PPP, Figure 1) to examine this largely unexplored mechanism of modulation of peptide function. We push the neuropeptide galanin through organotypic hippocampal slice ...

Computational Multiphysics to Optimize Humidification Chamber for a Novel PEM Fuel Cell Power System Used in Automobile Application - new

M. Raja[1]
[1]Tata Motors, Bengaluru, Karnataka, India

Proton Exchange Membrane (PEM) fuel cells are quickly becoming an attractive technology due to their ability to meet increasing energy demands in a cleaner, more efficient way compared to existing methods. A fuel cell is an electrochemical device which converts the chemical energy of a fuel and an oxidant directly into electricity without the intermediate step of classical, chemical combustion ...

Design Simulations of a General Purpose Research Micro Reactor for Methane Conversion to Syngas.

C. Bouchot[1], and M.A. Valenzuela[1]
[1]Instituto Politécnico Nacional-ESIQIE, México D.F, México

A general purpose stainless steel micro reactor setup for methane conversion is being designed for research purposes. We intend to design and build a modular device that would be able to manage different types of reactions depending on the installed modules. The device should be able to allow the study of gas phase reactions at low (atmospheric) and high pressures (up to 20 MPa), with the ...

Experimental Validation of Model of Electro-Chemical-Mechanical Planarization (ECMP) of Copper

J. Ebert[1], S. Ghosal[1], A. Emami-Naeini[1]
[1]SC Solutions, Sunnyvale, CA, USA

This paper describes the development of a COMSOL model of Electro-Chemical-Mechanical Planarization (ECMP) that was validated with experimental data. ECMP is used for processing of semiconductor wafers. We developed a 2D model of flow of phosphoric acid solution (the electrolyte) between two parallel plates that focuses on the physics and electrochemistry in ECMP. The model includes steady-state ...

Constructing COMSOL Models of a Bacteriological Fuel Cell

R. Coker[1], J. Mansell[1]
[1]NASA - Marshall Space Flight Center, Huntsville, AL, USA

We have started constructing preliminary design COMSOL models of a bacteriologically driven \'fuel cell\' that is intended to process waste products, such as carbon dioxide and brine, from a crewed vehicle. At this early stage, this complex system is reduced to two electrodes separated by a membrane. The electrolyte is a brine appropriate for growing methanogenic bateria, though none are ...

Advancements in Carbon Dioxide and Water Vapor Separations Using COMSOL Multiphysics®

J. Knox[1], R. Coker[1], R. Cummings[1], C. Gomez[1], G. Schunk[1]
[1]NASA, Marshall Space Flight Center, Huntsville, AL, USA

Some NASA efforts are focused on improving current systems that utilize fixed beds of sorbent pellets by evaluating structured sorbents, seeking more robust pelletized sorbents, and examining alternate bed configurations to improve system efficiency and reliability. For the bulk separation of CO2 and H2O, temperature changes due to the heat of adsorption are significant, requiring modeling and ...