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Liquid Chromatography

Application ID: 198

High-performance liquid chromatography (HPLC) is a common method of separating, identifying, and quantifying each chemical compound in a mixture. HPLC is found in the pharmaceutical, biotech, and food industries.

The Liquid Chromatography app simulates the separation of two species within a generic liquid chromatography column.

Simulations can help pinpoint design elements of chromatography columns and component separation details. This includes the length and porosity of the column and the specific conditions of the two components, including their Langmuir isotherm. All of this can be changed within the app.

This application is included as an example in the following products:


The combination of COMSOL® products required to model your application depends on several factors and may include boundary conditions, material properties, physics interfaces, and part libraries. Particular functionality may be common to several products. To determine the right combination of products for your modeling needs, review the 製品仕様一覧 and make use of a free evaluation license. The COMSOL Sales and Support teams are available for answering any questions you may have regarding this.