Production of Antibody–Drug Conjugates in a Stirred Tank Reactor

Application ID: 141911


This space-dependent model describes a stirred semibatch reactor used for producing antibody–drug conjugates. The reactor is set up in 3D and the conjugation reactions, turbulent flow, and concentration fields are simulated as functions of time. The resulting yield and drug-to-antibody ratio are compared to an ideal semibatch case.

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